Lipids and Atherosclerosis

Serum Lipids and Atherosclerosis

That hyperlipemia may be responsible for atherosclerosis has long been hypothecated on the grounds of what might be termed circumstantial evidence. The first experimental proof of this concept was provided by Anitschkow's demonstration in 1913 that atheroma can be produced in rabbits by feeding cholesterol. In recent years similar lesions have been induced by similar methods in five other speci...

Lipids and atherosclerosis

Atherosclerotic vascular disease is the cause of heart attacks, stroke, aortic aneurysms, and peripheral vascular disease, which together represent the most frequent causes of death in the industrialized world. Indeed, the aging of the population and the 'westernization' of world diet is predicted to increase the impact of atherosclerosis worldwide over the next few decades despite continuing a...

Plasma lipids and atherosclerosis.

Hyperlipidaemia may be defined as the presence of excess lipid in the blood. It may be classified according to the nature of the lipids which are increased. A classification of hyperlipidaemia based on the fasting levels of cholesterol and triglyceride allows of three possible abnormal groups, which are shown in table I together with the corresponding classification according to Fredrickson as ...

Blood lipids and human atherosclerosis.

Blood Lipids and Human Atherosclerosis

a transformation of the former group into the latter. Heparin administered to the rabbit l)events the usual buildup of high concentration of the Sf 10-50 lipoproteins (luring (clolestelol feeding anlld retards the develol)ment of atherosclerosis. In man, accompanying the re(listril)ution of lipoproteins, there was observed a marked reduction in angina pectoris in 55 of 59 Ipatienlts studied(l w...